Abstract：With the rapid development of the cold chain logistics industry, enterprises are paying more attention to the cost, quality of logistics services and carbon emissions generated by transportation. In order to solve this problem, a multi- depot half-open cold chain logistics routing optimization model is constructed, and various dynamic changes are integrated into the model. An improved NSGA-II algorithm is designed and the standard test function is used to prove that the algorithm has good convergence and diversity. The results show that, compared with the scheme without considering carbon emission, the distribution cost of the scheme with considering carbon emission increases by 19.00%, the transportation distance decreases by 5.16%, and the carbon emission cost decreases by 13.03%. Compared with the initial distribution scheme, the distribution cost of the real-time optimization scheme decreased by 29.78%, the carbon emission cost decreased by 23.19%, and the customer satisfaction increased by 14.49%. Compared with the single distribution center mode, the distribution cost of the multi-depot mode is reduced by 27.30%, the carbon emission cost is reduced by 48.89%, and the customer satisfaction is increased by 13.11%, which brings certain management enlightenment for cold chain logistics enterprises.
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