1. School of Systems Science, Beijing Normal University, Beijing 100875, China; 2. School of Statistics, Shanxi University of Finance and Economics, Taiyuan 030006, China; 3. New England Complex Systems Institute, Cambridge 02139, American; 4. Department of Chemistry, Brandeis University, Waltham 02453, American
Abstract：There is growing evidence that the current worldwide epidemic of COVID-19 has many asymptomatic infections. This raises new questions for the study of medical researchers, and it is also new challenge for non-medical interventions. Based on the SEIR model with periodic boundary, this study simulates the actual spread of pathogens and the interventions by multi-agent simulation. The simulations show that epidemic prevention and control can be feasible only with the joint intervention of the two measures when there are asymptomatic infections, one cannot leave without. Our results are of guiding importance for the prevention and control of epidemic situation in the world.
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